Endocrine Abstracts

Introduction: Multiple Endocrine Neoplasia Syndrome 2B (MEN 2B) is a very rare genetic disorder which affects the thyroid and the adrenal glands, the development of mucosal neuromas and the general appearance of the patient’s body. Therefore, we can encounter Medullary Thyroid Carcinomas (MTC), adrenal sympathetic paragangliomas (or Pheochromocytomas) and habitus Marfanoid. The disease represents a challenge for every clinician, especially if it occurs in a child.<p c...

Medullary thyroid carcinoma (MTC) is a rare malignancy arising from parafollicular C cells of the thyroid gland, sometimes due to germline mutations in the RET protooncogene. Testicular cancer is the most common malignancy in men aged 15 - 40 years with survival rates improved by the introduction of cisplatin therapy in the late 1970s. Nonetheless, platinum-based chemotherapy was shown to increase the risk of a solid second cancer with substantially increased site-specific ris...

Introduction: Ectopic ACTH syndromes account for 5–10% of Cushing syndrome, with intrathoracic and gastrointestinal–pancreatic neuroendocrine tumors being the most common causes, followed by small cell lung cancer, adrenal paraganglioma and medullary thyroid carcinoma.Case report: A 50-year-old male hypertensive and diabetic patient was transferred to our clinic for emergency endocrine care for hypokalemia. He had mild hypercortisolism and live...